COMPASSION. EXPERIENCE. RESPECT.
We Clean Tough Situations: Charleston Suicide, Crime Scene, Hoarding, and Biohazard Cleanup
Bio-One of Charleston helps families and communities after life’s most challenging moments. We clean what others can’t—biohazards, trauma, crime, and suicide scenes, hoarding, and more.
Our trained team shows up fast, works with care, and treats your space with respect.
- Available 24/7.
- Discreet arrival—unmarked vehicles upon request.
- We work with insurance.
- Locally owned and trusted.
Real help for real life: let us handle the cleanup, so you can focus on the path ahead.
Emergency response hotline
Get in touch with our 24/7 biohazard & crime scene cleaning team today
Dan was amazing. He was responsive, compassionate, and caring at a very hard time in my life. He answered immediately and him and his team were at my home within hours. I will always be...
Where Crisis Meets Compassion
Help first. Business second.
Hoarding Cleanup
We are here to earn your trust and ease you into the hoarding cleanup process.
Decomposition / Undiscovered Death
We handle the toughest scenes with dignity and compassion.
Medical Waste Disposal
We offer medical waste disposal and train others on its safe handling.
Emergency Vehicle Decontamination
We help protect first responders with deep, professional cleaning.
We respond 24/7.
Request a service now.
WE'RE READY 24/7
Work with us
Call Anytime—Day or Night
On-Site, With Care
You're in Good Hands
Ready For Anything 24/7/365
Call us anytime—24/7/365—for fast, compassionate service from a local Bio-One expert.
Why choose Bio-One of Charleston?
Trusted When It Matters Most
Because you deserve more than just a cleanup—you deserve care.
Families, property owners, and first responders choose Bio-One for fast, discreet, and compassionate cleanup.
People call us during some of their most challenging moments. We show up fast, listen first, and handle every scene skillfully and compassionately.
- Fast, local 24/7 response
- Trained experts who treat you with respect
- Discreet, thorough cleanup from start to finish
- We handle the insurance, so you don’t have to
We’re here to help you feel safe again—and we’ll walk with you every step of the way.
Your Local Cleanup Partner
Rooted in the community. Driven by compassion.
You can trust that when you call, you get real help from someone who truly understands.
Daniel and Hope Paffe
Daniel and Hope Paffe are the owners of Bio-One of Charleston. Both have spent most of their lives in Texas until recently moving to Charleston, SC. Hope spent the better part of the last twenty years as the owner/operator of a 48 bed Psychiatric facility specializing in the care of clients with Alzheimers, Dementia and Psychiatric conditions. Dan spent the last 25 years as the owner of various healthcare and laboratory related businesses, the latter specializing in forensic drugs of abuse testing. Both owners are excited about the opportunities to take their Bio-One franchise into the realm of clandestine laboratory cleanup utilizing high tech equipment and cleanup methodologies. They have recently signed a multi state agreement with a large federal drug agency to dismantle, bulk remove, transport and destruct clandestine laboratories and their material makeups. Dan and Hope have 7 children and their motto is to Livetired!
Real People. Real Compassion.
Our local team is trained, experienced, and here to help—no judgment, just support.
We understand that calling us means something serious has happened. That’s why our local Bio-One team brings more than training—we bring compassion, clear communication, and respect every step of the way.
- Highly trained and experienced technicians
- Honest, in-person estimates
- Discreet and professional service
- Locally owned and operated
You can count on us to handle it all—with care.
